TY - BOOK AU - edited by Dubel, Stefan AU - Reichert, Janice M. TI - Handbook of therapeutic antibodies: approved therapeutic antibodies and in vivo diagnostics : Volume 4 SN - 9783527329373 U1 - 615.37 DUB-S PY - 2014/// CY - Germany PB - Wiley Blackwell KW - Immunoglobulins--Biotechnology KW - Immunoglobulins--Therapeutic use KW - Immunopharmacology N1 - Still the most comprehensive reference source on the development, production and therapeutic application of antibodies, this second edition is thoroughly updated and now has 30% more content. Volume 1 covers selection and engineering strategies for new antibodies, while the second volume presents novel therapeutic concepts and antibodies in clinical study, as well as their potential. Volumes 3 and 4 feature detailed and specific information about each antibody approved for therapeutic purposes, including clinical data. This unique handbook concludes with a compendium of marketed monoclonal antibodies and an extensive index. Beyond providing current knowledge, the authors discuss emerging technologies, future developments, and intellectual property issues, such that this handbook meets the needs of academic researchers, decision makers in industry and healthcare professionals in the clinic ER -