"The inspiring memoir of a young doctor and former college athlete who became a champion for people suffering from rare, under-researched diseases--all while battling his own. A former Georgetown quarterback nicknamed 'The Beast,' David Fajgenbaum was also a force in medical school, where he was known for his unmatched mental stamina. But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing, and he was read his last rites. Doctors were baffled over a condition they had yet even to diagnose; floating in and out of consciousness, Fajgenbaum prayed for the equivalent of game day overtime: a second chance. Miraculously, Fajgenbaum survived, but only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease--an extraordinarily deadly and rare condition that acts like a cross between cancer and autoimmune disease. When he relapsed on the only drug in development and realised that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action. Between hospitalisations, he studied his charts and tested his blood samples, looking for clues that could unlock a new treatment. With the help of family, friends and mentors, he also reached out to other Castleman disease patients and physicians and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them; instead of waiting for the scientific stars to align, he proposed to align them himself. More than five years later and now married to his college sweetheart, his hard work has paid off: a treatment that he identified has induced a tentative remission. His novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope and what can happen when forces of determination, love, family, faith and fate collide