Structure-based ligand design edited by Klaus Gubernator and Hans-Joachim Bohm

By:

Gubernator, Klaus

Contributor(s):

Böhm, Hans-Joachim

Material type: Text

TextSeries: Methods and principles in medicinal chemistry ; v.6Publication details: New York Wiley VCH 1998Description: 153pISBN:

9788126579587

Subject(s):

DDC classification:

615.7 GUB-K

Average rating: 0.0 (0 votes)

Holdings
Item type	Current library	Collection	Shelving location	Call number	Status	Date due	Barcode	Item holds
Books	BITS Pilani Hyderabad	610	General Stack (For lending)	615.7 GUB-K (Browse shelf(Opens below))	Available		42063

Total holds: 0

Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic paradigm of structure-based ligand design. Although this method first emerged in the 1980s, it has already become a powerful tool for pharmaceutical research. Much has been learned, however, since the first attempts to discover drugs on the basis of available biochemical and structural data. Nowadays, structure-based ligand design is an established method for creating drugs with new structural features, for modifying binding activities and pharmaco.

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