In the new millennium, the shape of India’s vibrant entrepreneurial economy has changed significantly to move towards one driven by technology and innovation. Today, India is one of the largest start-up and innovation hubs in the world, and the Indian start-up ecosystem has become an important contributor in our journey to become a $5 trillion economy. Shifting Orbits Italic text chronicles the spectacular rise of the start-up landscape in India in four different sections: innovation, incubation, funding and industry perspectives. • The first section dives deeper into understanding how India is faring on innovation-led entrepreneurship and delineates the challenges to be overcome. • The next section explains how incubators provide a safe harbour for start-ups so that they can survive and flourish as viable businesses. • For start-ups to be able to grow and create an impact, funding is critical – the third section examines the current funding scenario and lists the policy changes essential for its growth. • The section on industry perspectives takes an analytical, practice-centred view of the growth of the Indian innovation ecosystem. Taken together, Shifting Orbits is a comprehensive narrative on innovation and venturing in India and provides valuable insights on current trends and practices as well as the challenges and potential benefits for the future.